CHMP2B

Across TCGA patient cohorts, CHMP2B protein abundance is significantly associated with the RNA expression of many other genes, with 10,860 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHMP2B-associated genes across cancer lineages are CDC42, C3orf38, and CHD6. Each is linked with CHMP2B in more than 3 cancer types. Because this analysis shows association rather than direction, both CHMP2B-to-partner and partner-to-CHMP2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP2B versus CDC42 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP2B→partner) and Y-score (partner→CHMP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDC42 →	+0.481	+0.322	.004	.001	3	4
BRCA	C3orf38 →	+0.421	+0.377	.001	.006	3	4
LSCC	CHD6 →	-0.503	-0.217	<.001	<.001	3	4
HNSC	RPL12P11 →	-0.650	-0.259	.002	.004	3	4
BRCA	CPE →	+1.256	+0.361	<.001	.008	3	3
BRCA	LGALS8 →	+0.675	+0.456	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,860 associations by consensus.

CHMP2B vs CDC42 — OV

Explore this scatter interactively →