CHMP1B

Across TCGA patient cohorts, CHMP1B protein abundance is significantly associated with the RNA expression of many other genes, with 12,586 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHMP1B-associated genes across cancer lineages are AFG3L2, ZNF24, and NAPG. Each is linked with CHMP1B in more than 5 cancer types. Because this analysis shows association rather than direction, both CHMP1B-to-partner and partner-to-CHMP1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP1B versus AFG3L2 in LSCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP1B→partner) and Y-score (partner→CHMP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AFG3L2 →	+0.686	+0.452	<.001	<.001	3	6
OV	ZNF24 →	+0.630	+0.353	<.001	.003	3	6
LSCC	NAPG →	+0.592	+0.472	<.001	<.001	3	5
PDAC	MPPE1 →	+0.527	+0.475	<.001	<.001	3	5
LUAD	VAPA →	+0.487	+0.301	<.001	<.001	3	5
OV	PSMG2 →	+0.490	+0.415	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,586 associations by consensus.

CHMP1B vs AFG3L2 — LSCC

Explore this scatter interactively →