CHMP1B

Across TCGA cell cohorts, CHMP1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,631 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHMP1B-associated GO terms across cancer lineages are Multivesicular body-lysosome fusion, Lysosomal membrane organization, and Vesicle fusion with vacuole. Each is linked with CHMP1B in more than 16 cancer types. Because this analysis shows association rather than direction, both CHMP1B-to-partner and partner-to-CHMP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multivesicular body-lysosome fusion grouped by CHMP1B-low versus CHMP1B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP1B→partner) and Y-score (partner→CHMP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Multivesicular body-lysosome fusion →	+0.166	+1.204	<.001	<.001	3	17
PANCREAS	Lysosomal membrane organization →	+0.113	+0.929	<.001	<.001	3	17
STOMACH	Vesicle fusion with vacuole →	+0.162	+1.204	<.001	<.001	3	17
OESOPHAGUS	Process utilizing autophagic mechanism →	+0.076	+1.240	<.001	<.001	3	15
OESOPHAGUS	Autophagy →	+0.076	+1.240	<.001	<.001	3	15
SOFT_TISSUE	Autophagosome maturation →	+0.084	+0.845	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,631 associations by consensus.

Multivesicular body-lysosome fusion by CHMP1B expression — STOMACH

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