CHMP1A

Across TCGA pan-cancer cohorts, CHMP1A mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CHMP1A’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where CHMP1A mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types CHMP1A is over-expressed in tumor.

CCRCC, PDAC, and LUAD are the cancer types where CHMP1A tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CHMP1A mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	Female	All	+0.367	<.001	11	view →
PDAC	Female	II,III,IV	+1.094	<.001	8	view →
LUAD	Male	II,III,IV	+0.285	<.001	8	view →
LSCC	All	II,III,IV	+0.234	<.001	6	view →
HNSC	All	III,IV	+0.147	.016	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CHMP1A–CCRCC

Open the CCRCC breakdown →