CHMP1A

Across TCGA patient cohorts, CHMP1A mutation is significantly associated with the RNA expression of many other genes, with 238 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHMP1A-associated genes across cancer lineages are LINC01276, RN7SL478P, and HMGN1P28. Each is linked with CHMP1A in more than 1 cancer types. Because this analysis shows association rather than direction, both CHMP1A-to-partner and partner-to-CHMP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01276 grouped by CHMP1A-low versus CHMP1A-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP1A→partner) and Y-score (partner→CHMP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	LINC01276 →	+0.074	+4.478	<.001	.005	3	2
LGG	RN7SL478P →	+0.174	+4.742	<.001	.003	3	2
COAD	HMGN1P28 →	+0.329	+3.627	<.001	.008	3	2
COAD	BCAR1P2 →	+0.160	+3.588	<.001	.007	3	2
UCEC	LINC01707 →	+0.216	+2.838	<.001	.001	3	2
KIRP	FTMT →	+0.079	+4.967	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 238 associations by consensus.

LINC01276 by CHMP1A expression — LGG

Explore this box plot interactively →