CHMP1A

Across TCGA cell cohorts, CHMP1A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,363 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHMP1A-associated GO terms across cancer lineages are mRNA alternative polyadenylation, mRNA transport, and Basolateral protein secretion. Each is linked with CHMP1A in more than 13 cancer types. Because this analysis shows association rather than direction, both CHMP1A-to-partner and partner-to-CHMP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by CHMP1A-low versus CHMP1A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP1A→partner) and Y-score (partner→CHMP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	mRNA alternative polyadenylation →	+0.092	+1.047	.001	.001	3	14
BREAST	mRNA transport →	+0.083	+0.923	.007	.001	3	14
BREAST	Basolateral protein secretion →	+0.128	+0.875	<.001	<.001	3	14
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.087	+0.964	.002	.001	3	13
BREAST	Mitotic G1 DNA damage checkpoint signaling →	+0.146	+1.018	<.001	<.001	3	13
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.138	+0.750	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,363 associations by consensus.

mRNA alternative polyadenylation by CHMP1A expression — BREAST

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