Across TCGA patient cohorts, CHML RNA expression is significantly associated with the protein abundance of many other proteins, with 15,657 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHML-associated proteins across cancer lineages are CDC73, IPO9, and GATAD2B. Each is linked with CHML in more than 6 cancer types. Because this analysis shows association rather than direction, both CHML-to-partner and partner-to-CHML results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHML→partner) and Y-score (partner→CHML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDC73 →	+0.260	+0.952	<.001	<.001	3	7
BRCA	IPO9 →	+0.404	+0.672	<.001	<.001	3	7
GBM	GATAD2B →	+0.383	+0.642	.001	.002	3	7
BRCA	ADSS2 →	+0.271	+0.727	<.001	<.001	3	6
LSCC	CCDC167_S42 →	+0.872	+0.859	<.001	<.001	3	6
LUAD	ECT2_T359 →	+1.037	+0.715	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,657 associations by consensus.

Exploration

CHML survival (RNA) · tumor vs normal (RNA) · all CHML data types