Across TCGA patient cohorts, CHM protein abundance is significantly associated with the protein abundance of many other proteins, with 18,428 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHM-associated proteins across cancer lineages are MAPKAPK3, PATZ1, and RIN3. Each is linked with CHM in more than 5 cancer types. Because this analysis shows association rather than direction, both CHM-to-partner and partner-to-CHM results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHM→partner) and Y-score (partner→CHM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAPKAPK3 →	+0.281	+0.173	<.001	.001	3	6
OV	PATZ1 →	-0.648	-0.465	<.001	<.001	3	5
LSCC	RIN3 →	+0.334	+0.186	<.001	<.001	3	5
PDAC	SMARCA5_S66 →	-0.698	-0.350	<.001	<.001	3	5
PDAC	SMARCC2_S347 →	-0.902	-0.215	<.001	<.001	3	5
COAD	EFHD2 →	+0.696	+0.307	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,428 associations by consensus.

Exploration

CHM survival (RNA) · tumor vs normal (RNA) · all CHM data types