CHKB-CPT1B

Across TCGA patient cohorts, CHKB-CPT1B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CHKB-CPT1B-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Regulation of mRNA export from nucleus, and Steroid hormone mediated signaling pathway. Each is linked with CHKB-CPT1B in more than 31 cancer types. Because this analysis shows association rather than direction, both CHKB-CPT1B-to-partner and partner-to-CHKB-CPT1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by CHKB-CPT1B-low versus CHKB-CPT1B-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHKB-CPT1B→partner) and Y-score (partner→CHKB-CPT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.063	+0.943	<.001	<.001	3	32
DLBC	Regulation of mRNA export from nucleus →	+0.097	+1.037	<.001	<.001	3	31
DLBC	Steroid hormone mediated signaling pathway →	+0.050	+0.732	<.001	<.001	3	31
KIRC	Obsolete ncRNA export from nucleus →	+0.083	+0.627	<.001	<.001	3	31
DLBC	Protein demethylation →	+0.108	+0.667	<.001	<.001	3	31
DLBC	snRNA metabolic process →	+0.062	+0.869	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by CHKB-CPT1B expression — UCS

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