CHIC2

Across TCGA patient cohorts, CHIC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,700 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CHIC2-associated proteins across cancer lineages are MALSU1, VCL, and MRPL24. Each is linked with CHIC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHIC2-to-partner and partner-to-CHIC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHIC2 versus MALSU1 in OV, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHIC2→partner) and Y-score (partner→CHIC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MALSU1 →	-0.501	-0.665	.002	<.001	3	5
CCRCC	VCL →	+0.463	+0.288	<.001	<.001	3	5
PDAC	MRPL24 →	-0.356	-0.258	<.001	.005	3	5
COAD	PMPCA →	-0.371	-0.336	<.001	<.001	3	4
PDAC	PPM1F →	+0.311	+0.336	<.001	<.001	3	4
CCRCC	PYCR2 →	-0.504	-0.272	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,700 associations by consensus.

CHIC2 vs MALSU1 — OV

Explore this scatter interactively →