CHIAP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHIAP2 mutation is significantly associated with the RNA expression of many other genes, with 1,410 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHIAP2-associated genes across cancer lineages are AEN, TCEA1P4, and KCTD7. Each is linked with CHIAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHIAP2-to-partner and partner-to-CHIAP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHIAP2→partner) and Y-score (partner→CHIAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAEN →+0.672+2.928<.001.00132
UCECTCEA1P4 →+0.356+3.364<.001.00432
UCECKCTD7 →+0.483+4.010.001<.00132
UCECUBAP1L →+0.512+3.524<.001.00232
UCECRN7SKP295 →+0.198+2.541<.001.00732
UCECNEDD4L →+0.526+3.500.003.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,410 associations by consensus.

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