CHIAP1

Across TCGA pan-cancer cohorts, CHIAP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CHIAP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CHIAP1 RNA is repressed in tumor relative to normal tissue. In most cancer types CHIAP1 is over-expressed in tumor, although a few such as LUAD and HNSC show the opposite, repressed pattern.

LUAD, HNSC, and LUSC are the cancer types where CHIAP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CHIAP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	−0.127	<.001	5	view →
HNSC	Male	All	−0.049	.023	4	view →
LUSC	All	All	−0.122	.003	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CHIAP1–LUAD

Open the LUAD breakdown →