CHI3L1

Across TCGA patient cohorts, CHI3L1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,231 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHI3L1-associated proteins across cancer lineages are PARVG, CEBPB, and THEMIS2. Each is linked with CHI3L1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CHI3L1-to-partner and partner-to-CHI3L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHI3L1 versus PARVG in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHI3L1→partner) and Y-score (partner→CHI3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PARVG →	+0.516	+1.663	<.001	<.001	3	8
BRCA	CEBPB →	+0.676	+2.026	<.001	<.001	3	8
UCEC	THEMIS2 →	+0.677	+1.352	<.001	.003	3	8
GBM	PTPN6 →	+0.548	+1.840	<.001	<.001	3	7
UCEC	WAS →	+0.590	+1.400	<.001	<.001	3	7
GBM	MYO1G →	+0.567	+1.784	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,231 associations by consensus.

CHI3L1 vs PARVG — GBM

Explore this scatter interactively →