CHGA

Across TCGA patient cohorts, CHGA RNA expression is significantly associated with the protein abundance of many other proteins, with 18,036 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHGA-associated proteins across cancer lineages are CHGA_S322, MAP1A_S2022, and MAP1A_S2106. Each is linked with CHGA in more than 4 cancer types. Because this analysis shows association rather than direction, both CHGA-to-partner and partner-to-CHGA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHGA versus CHGA_S322 in OV, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHGA→partner) and Y-score (partner→CHGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CHGA_S322 →	+1.854	+3.218	.004	.006	3	5
LSCC	MAP1A_S2022 →	+0.691	+0.779	.003	.002	3	4
UCEC	MAP1A_S2106 →	+0.668	+2.405	.001	.001	3	4
UCEC	CHGA_S333 →	+2.024	+3.499	<.001	<.001	3	4
GBM	CHGB →	+1.305	+2.479	<.001	<.001	3	4
BRCA	CHGB_S391 →	+1.263	+0.925	.002	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,036 associations by consensus.

CHGA vs CHGA_S322 — OV

Explore this scatter interactively →