Across TCGA patient cohorts, CHEK2P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 129 significant associations in total. OV shows the largest number of these associations.

The most reproducible CHEK2P4-associated GO terms across cancer lineages are Negative regulation of transcription regulatory region DNA binding, Vesicle uncoating, and Long-term synaptic potentiation. Each is linked with CHEK2P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHEK2P4-to-partner and partner-to-CHEK2P4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHEK2P4→partner) and Y-score (partner→CHEK2P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	Negative regulation of transcription regulatory region DNA binding →	+0.033	+0.019	<.001	<.001	3	1
BRCA	Vesicle uncoating →	+0.034	+0.018	.006	<.001	3	1
OV	Long-term synaptic potentiation →	-0.031	-0.027	<.001	.002	3	1
OV	Cellular lipid biosynthetic process →	-0.036	-0.018	.003	<.001	3	1
ACC	Regulation of calcidiol 1-monooxygenase activity →	+0.118	+0.159	<.001	.004	3	1
ACC	Serine family amino acid metabolic process →	+0.026	+0.108	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 129 associations by consensus.

Exploration

CHEK2P4 survival (RNA) · tumor vs normal (RNA) · all CHEK2P4 data types