CHEK2P3

Across TCGA patient cohorts, CHEK2P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,764 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CHEK2P3-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Positive regulation of dendritic spine development, and Positive regulation of canonical Wnt signaling pathway. Each is linked with CHEK2P3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHEK2P3-to-partner and partner-to-CHEK2P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of post-translational protein modification grouped by CHEK2P3-low versus CHEK2P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHEK2P3→partner) and Y-score (partner→CHEK2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of post-translational protein modification →	+0.108	+0.099	<.001	<.001	3	5
STAD	Positive regulation of dendritic spine development →	+0.054	+0.107	<.001	<.001	3	5
STAD	Positive regulation of canonical Wnt signaling pathway →	+0.080	+0.098	<.001	<.001	3	4
UCEC	Mesenchymal cell migration →	+0.058	+0.034	<.001	<.001	3	4
STAD	Obsolete ncRNA transcription →	+0.101	+0.098	<.001	<.001	3	4
STAD	Obsolete negative regulation of mitochondrion organization →	+0.089	+0.097	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,764 associations by consensus.

Regulation of post-translational protein modification by CHEK2P3 expression — STAD

Explore this box plot interactively →