CHEK2P2

Across TCGA patient cohorts, CHEK2P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,906 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CHEK2P2-associated GO terms across cancer lineages are Mitochondrial gene expression, Cellular respiration, and Mitochondrial translation. Each is linked with CHEK2P2 in more than 12 cancer types. Because this analysis shows association rather than direction, both CHEK2P2-to-partner and partner-to-CHEK2P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by CHEK2P2-low versus CHEK2P2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHEK2P2→partner) and Y-score (partner→CHEK2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.073	+0.436	<.001	<.001	3	13
STAD	Cellular respiration →	+0.067	+0.374	<.001	<.001	3	13
STAD	Mitochondrial translation →	+0.074	+0.381	<.001	<.001	3	13
ESCA	Positive regulation of telomerase RNA localization to Cajal body →	+0.075	+0.340	<.001	.002	3	12
ESCA	Aerobic respiration →	+0.076	+0.400	<.001	<.001	2	13
STAD	Nucleoside phosphate biosynthetic process →	+0.053	+0.352	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,906 associations by consensus.

Mitochondrial gene expression by CHEK2P2 expression — STAD

Explore this box plot interactively →