CHD9

Across TCGA patient cohorts, CHD9 protein abundance is significantly associated with the RNA expression of many other genes, with 2,979 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHD9-associated genes across cancer lineages are ARL2BP, PMCHL2, and ZNF596. Each is linked with CHD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHD9-to-partner and partner-to-CHD9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD9 versus ARL2BP in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD9→partner) and Y-score (partner→CHD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARL2BP →	+0.700	+0.196	<.001	.005	3	2
PDAC	PMCHL2 →	-0.267	-1.114	.005	.003	3	2
PDAC	ZNF596 →	-0.395	-1.052	.005	.007	3	2
LSCC	ZNF626 →	-0.544	-0.190	<.001	<.001	3	2
PDAC	HSPD1P11 →	-0.596	-1.127	.004	.002	3	2
LSCC	LMO3 →	-1.367	-0.192	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,979 associations by consensus.

CHD9 vs ARL2BP — LSCC

Explore this scatter interactively →