CHD7

Across TCGA patient cohorts, CHD7 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,727 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHD7-associated proteins across cancer lineages are CHD7_S1874, ADNP, and CHD7_S2559. Each is linked with CHD7 in more than 8 cancer types. Because this analysis shows association rather than direction, both CHD7-to-partner and partner-to-CHD7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD7 versus CHD7_S1874 in GBM, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD7→partner) and Y-score (partner→CHD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CHD7_S1874 →	+0.915	+0.955	<.001	<.001	3	9
GBM	ADNP →	+0.375	+0.749	<.001	<.001	3	7
HNSC	CHD7_S2559 →	+0.631	+0.732	<.001	<.001	3	7
BRCA	CHD7_S2956 →	+0.972	+0.870	<.001	<.001	3	7
LUAD	HMGB3 →	+0.822	+0.574	<.001	.001	3	7
LSCC	PSMB10 →	-0.461	-0.570	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,727 associations by consensus.

CHD7 vs CHD7_S1874 — GBM

Explore this scatter interactively →