CHD7

Across TCGA patient cohorts, CHD7 protein abundance is significantly associated with the RNA expression of many other genes, with 14,628 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHD7-associated genes across cancer lineages are DSCC1, E2F1, and RECQL4. Each is linked with CHD7 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHD7-to-partner and partner-to-CHD7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD7 versus DSCC1 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD7→partner) and Y-score (partner→CHD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DSCC1 →	+0.947	+0.614	<.001	<.001	3	6
GBM	E2F1 →	+1.264	+0.613	<.001	<.001	3	5
COAD	RECQL4 →	+1.083	+0.734	<.001	.005	3	5
BRCA	UBE2C →	+1.508	+0.600	<.001	<.001	3	5
BRCA	BOP1 →	+0.971	+0.547	<.001	<.001	3	5
BRCA	TPX2 →	+1.238	+0.555	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,628 associations by consensus.

CHD7 vs DSCC1 — OV

Explore this scatter interactively →