CHD5

Across TCGA patient cohorts, CHD5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,029 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHD5-associated genes across cancer lineages are CACNA1I, CRYM, and PRSS3. Each is linked with CHD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHD5-to-partner and partner-to-CHD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD5 versus CACNA1I in GBM, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD5→partner) and Y-score (partner→CHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CACNA1I →	+0.845	+0.629	.007	.004	3	1
GBM	CRYM →	+1.506	+0.483	.004	<.001	3	1
GBM	PRSS3 →	+0.619	+0.477	<.001	.003	3	1
GBM	SLC17A7 →	+1.715	+0.415	.007	.005	3	1
GBM	PITX3 →	+0.194	+0.665	.003	.007	3	1
GBM	ASIC2 →	+0.577	+0.739	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,029 associations by consensus.

CHD5 vs CACNA1I — GBM

Explore this scatter interactively →