CHD5

Across TCGA cell cohorts, CHD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,781 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CHD5-associated GO terms across cancer lineages are DNA-templated transcription initiation, Positive regulation of telomerase RNA localization to Cajal body, and Positive regulation of translation. Each is linked with CHD5 in more than 9 cancer types. Because this analysis shows association rather than direction, both CHD5-to-partner and partner-to-CHD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by CHD5-low versus CHD5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD5→partner) and Y-score (partner→CHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DNA-templated transcription initiation →	+0.067	+0.701	<.001	.005	3	9
LARGE_INTESTINE	Positive regulation of telomerase RNA localization to Cajal body →	+0.055	+0.464	<.001	.002	3	9
LARGE_INTESTINE	Positive regulation of translation →	+0.059	+0.847	<.001	.003	3	9
OVARY	Transcription initiation at RNA polymerase II promoter →	+0.052	+1.014	<.001	.001	3	9
LUNG_NSCLC_LUAD	Protein-DNA complex assembly →	+0.055	+0.656	<.001	<.001	3	9
BLOOD_Leukemia	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.078	+1.375	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,781 associations by consensus.

DNA-templated transcription initiation by CHD5 expression — STOMACH

Explore this box plot interactively →