CHD4

Across TCGA patient cohorts, CHD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,966 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHD4-associated proteins across cancer lineages are ADNP, HDAC2, and SMARCC2. Each is linked with CHD4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHD4-to-partner and partner-to-CHD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD4 versus ADNP in HNSC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD4→partner) and Y-score (partner→CHD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ADNP →	+0.354	+0.433	<.001	.005	3	6
LSCC	HDAC2 →	+0.346	+0.302	<.001	<.001	3	6
GBM	SMARCC2 →	+0.371	+0.255	<.001	<.001	3	5
GBM	BOD1L1 →	+0.190	+0.191	.001	<.001	3	5
GBM	CELF1 →	+0.245	+0.184	.002	.002	3	5
HNSC	HNRNPLL →	+0.255	+0.352	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,966 associations by consensus.

CHD4 vs ADNP — HNSC

Explore this scatter interactively →