CHD2

Across TCGA patient cohorts, CHD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,072 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHD2-associated proteins across cancer lineages are CPNE2, GABPA, and PRPF38A. Each is linked with CHD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CHD2-to-partner and partner-to-CHD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD2 versus CPNE2 in GBM, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD2→partner) and Y-score (partner→CHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CPNE2 →	+0.407	+0.287	<.001	<.001	3	4
GBM	GABPA →	+0.223	+0.255	.003	<.001	3	4
GBM	PRPF38A →	+0.238	+0.235	<.001	<.001	3	4
GBM	XRCC6 →	+0.217	+0.163	<.001	.008	3	4
GBM	NFIA →	+0.464	+0.323	<.001	<.001	3	4
LSCC	VPS9D1_S116 →	-0.542	-0.259	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,072 associations by consensus.

CHD2 vs CPNE2 — GBM

Explore this scatter interactively →