CHD2

Across TCGA patient cohorts, CHD2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,578 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHD2-associated genes across cancer lineages are MTA1, PRC1-AS1, and GAS5. Each is linked with CHD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHD2-to-partner and partner-to-CHD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD2 versus MTA1 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD2→partner) and Y-score (partner→CHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MTA1 →	+0.775	+0.220	<.001	.001	3	5
GBM	PRC1-AS1 →	+0.585	+0.215	<.001	<.001	3	5
LUAD	GAS5 →	+0.612	+0.192	.002	<.001	3	5
GBM	ZNF410 →	+0.367	+0.238	<.001	<.001	3	4
OV	C15orf40 →	+0.469	+0.181	.004	.003	3	4
OV	BRF1 →	+0.413	+0.164	.004	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,578 associations by consensus.

CHD2 vs MTA1 — OV

Explore this scatter interactively →