CHCHD5

Across TCGA patient cohorts, CHCHD5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,786 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHCHD5-associated genes across cancer lineages are SLC43A1, GPHA2, and SRSF12. Each is linked with CHCHD5 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHCHD5-to-partner and partner-to-CHCHD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHCHD5 versus SLC43A1 in PDAC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD5→partner) and Y-score (partner→CHCHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SLC43A1 →	-0.606	-0.503	<.001	<.001	3	3
PDAC	GPHA2 →	-1.264	-0.705	<.001	<.001	3	3
BRCA	SRSF12 →	-0.741	-0.452	.001	<.001	3	3
COAD	ZNF503 →	-1.165	-0.712	.002	.001	3	3
BRCA	HORMAD1 →	-1.744	-0.328	<.001	<.001	3	2
GBM	HMGN2P9 →	+0.415	+0.427	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,786 associations by consensus.

CHCHD5 vs SLC43A1 — PDAC

Explore this scatter interactively →