CHCHD5

Across TCGA cell cohorts, CHCHD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,590 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHCHD5-associated GO terms across cancer lineages are Cellular response to toxic substance, Cellular detoxification, and miRNA processing. Each is linked with CHCHD5 in more than 7 cancer types. Because this analysis shows association rather than direction, both CHCHD5-to-partner and partner-to-CHCHD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to toxic substance grouped by CHCHD5-low versus CHCHD5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD5→partner) and Y-score (partner→CHCHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cellular response to toxic substance →	+0.083	+0.736	<.001	<.001	3	8
BONE	Cellular detoxification →	+0.090	+0.755	<.001	<.001	3	7
PANCREAS	miRNA processing →	-0.062	-0.438	.001	<.001	3	6
BREAST	Positive regulation of vascular associated smooth muscle cell apoptotic process →	-0.106	-0.583	.001	.004	3	6
BLOOD_Lymphoma	Nucleic acid catabolic process →	-0.043	-0.619	.002	.001	3	5
BLOOD_Lymphoma	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	-0.050	-0.416	.005	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,590 associations by consensus.

Cellular response to toxic substance by CHCHD5 expression — BONE

Explore this box plot interactively →