CHCHD10

Across TCGA cell cohorts, CHCHD10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,635 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHCHD10-associated GO terms across cancer lineages are Ubiquinone metabolic process, Proteinogenic amino acid metabolic process, and Mitochondrial respiratory chain complex assembly. Each is linked with CHCHD10 in more than 9 cancer types. Because this analysis shows association rather than direction, both CHCHD10-to-partner and partner-to-CHCHD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ubiquinone metabolic process grouped by CHCHD10-low versus CHCHD10-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD10→partner) and Y-score (partner→CHCHD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Ubiquinone metabolic process →	+0.099	+1.826	<.001	<.001	3	10
LARGE_INTESTINE	Proteinogenic amino acid metabolic process →	+0.088	+1.040	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Mitochondrial respiratory chain complex assembly →	+0.086	+1.620	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Mitochondrial membrane organization →	+0.080	+1.539	<.001	<.001	3	9
LIVER	Sulfur compound catabolic process →	+0.131	+2.549	<.001	<.001	3	9
BLOOD_Myeloma	Mitochondrial disulfide relay system →	+0.132	+1.092	.002	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,635 associations by consensus.

Ubiquinone metabolic process by CHCHD10 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →