Across TCGA patient cohorts, CHAMP1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,913 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHAMP1-associated genes across cancer lineages are GAS5, PCID2, and CHTOP. Each is linked with CHAMP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CHAMP1-to-partner and partner-to-CHAMP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAMP1→partner) and Y-score (partner→CHAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GAS5 →	+1.061	+0.328	<.001	<.001	3	9
OV	PCID2 →	+0.564	+0.448	<.001	<.001	3	8
LSCC	CHTOP →	+0.547	+0.324	<.001	<.001	3	8
HNSC	PMF1 →	+0.564	+0.335	<.001	<.001	3	8
HNSC	LYSMD1 →	+0.748	+0.293	<.001	<.001	3	8
GBM	UPF3A →	+0.568	+0.424	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,913 associations by consensus.

Exploration

CHAMP1 survival (RNA) · tumor vs normal (RNA) · all CHAMP1 data types