Across TCGA patient cohorts, CHAMP1 mutation is significantly associated with the RNA expression of many other genes, with 3,933 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHAMP1-associated genes across cancer lineages are RNA5SP405, RNU6-537P, and NIFKP9. Each is linked with CHAMP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHAMP1-to-partner and partner-to-CHAMP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAMP1→partner) and Y-score (partner→CHAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP405 →	+0.206	+2.827	<.001	.002	3	3
KIRP	RNU6-537P →	+0.322	+4.628	.004	.007	3	2
SKCM	NIFKP9 →	+0.078	+3.098	.002	.008	3	2
BRCA	RNU6-974P →	+0.343	+8.471	<.001	.005	3	2
LUAD	H3C15 →	+0.026	+3.906	<.001	.001	3	2
UCEC	TOMM22P5 →	+0.185	+1.669	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,933 associations by consensus.

Exploration

CHAMP1 survival (RNA) · tumor vs normal (RNA) · all CHAMP1 data types