CHAD

Across TCGA patient cohorts, CHAD RNA expression is significantly associated with the protein abundance of many other proteins, with 13,817 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHAD-associated proteins across cancer lineages are ACSF2, RPL5, and MKI67. Each is linked with CHAD in more than 7 cancer types. Because this analysis shows association rather than direction, both CHAD-to-partner and partner-to-CHAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHAD versus ACSF2 in COAD, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAD→partner) and Y-score (partner→CHAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ACSF2 →	+0.610	+0.489	<.001	<.001	3	8
BRCA	RPL5 →	-0.230	-2.003	<.001	<.001	3	5
BRCA	MKI67 →	-0.697	-1.566	<.001	<.001	3	5
BRCA	PLIN5_S140 →	+1.468	+1.430	<.001	<.001	3	4
BRCA	UTRN →	+0.216	+1.347	<.001	<.001	3	4
LUAD	FCHSD2_S675 →	+0.582	+1.095	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,817 associations by consensus.

CHAD vs ACSF2 — COAD

Explore this scatter interactively →