CHAC2

Across TCGA patient cohorts, CHAC2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,938 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHAC2-associated genes across cancer lineages are RPS27L, C1QTNF7, and FAM83D. Each is linked with CHAC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHAC2-to-partner and partner-to-CHAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHAC2 versus RPS27L in BRCA, with a Pearson correlation of -0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAC2→partner) and Y-score (partner→CHAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPS27L →	-0.443	-0.297	.002	.007	3	5
UCEC	C1QTNF7 →	-0.729	-0.400	<.001	<.001	3	5
HNSC	FAM83D →	+1.102	+0.481	<.001	<.001	3	4
UCEC	NUDT1 →	+0.789	+0.395	.004	.002	3	4
LSCC	EZH2 →	+0.955	+0.583	<.001	<.001	3	4
UCEC	CENPA →	+1.021	+0.503	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,938 associations by consensus.

CHAC2 vs RPS27L — BRCA

Explore this scatter interactively →