CHAC1

Across TCGA patient cohorts, CHAC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,977 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHAC1-associated proteins across cancer lineages are ASNS, GARS1, and PSAT1. Each is linked with CHAC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CHAC1-to-partner and partner-to-CHAC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHAC1 versus ASNS in BRCA, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAC1→partner) and Y-score (partner→CHAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ASNS →	+0.718	+1.124	<.001	<.001	3	9
BRCA	GARS1 →	+0.402	+1.093	<.001	<.001	3	7
BRCA	PSAT1 →	+1.186	+1.344	<.001	<.001	3	6
COAD	YARS1 →	+0.362	+0.751	<.001	<.001	3	5
BRCA	CARS1 →	+0.183	+0.988	<.001	<.001	3	4
COAD	PPIB →	+0.349	+0.817	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,977 associations by consensus.

CHAC1 vs ASNS — BRCA

Explore this scatter interactively →