CGREF1

Across TCGA patient cohorts, CGREF1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,747 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CGREF1-associated genes across cancer lineages are PODXL2, DIRAS1, and GAREM2. Each is linked with CGREF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CGREF1-to-partner and partner-to-CGREF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CGREF1 versus PODXL2 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGREF1→partner) and Y-score (partner→CGREF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PODXL2 →	+1.680	+0.862	<.001	<.001	3	3
GBM	DIRAS1 →	+0.715	+0.533	.001	.001	3	3
UCEC	GAREM2 →	+0.629	+0.760	<.001	<.001	3	3
LSCC	LINC01703 →	+0.654	+0.680	.002	<.001	3	3
LSCC	EEF1A2 →	+1.358	+0.624	.004	.001	3	2
HNSC	ABCD1 →	-0.553	-0.618	.008	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,747 associations by consensus.

CGREF1 vs PODXL2 — HNSC

Explore this scatter interactively →