CGREF1

Across TCGA cell cohorts, CGREF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,595 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CGREF1-associated GO terms across cancer lineages are Purine nucleotide biosynthetic process, Nucleoside triphosphate metabolic process, and Nucleotide biosynthetic process. Each is linked with CGREF1 in more than 10 cancer types. Because this analysis shows association rather than direction, both CGREF1-to-partner and partner-to-CGREF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleotide biosynthetic process grouped by CGREF1-low versus CGREF1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CGREF1→partner) and Y-score (partner→CGREF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Purine nucleotide biosynthetic process →	+0.076	+1.925	<.001	<.001	3	11
SKIN	Nucleoside triphosphate metabolic process →	+0.073	+1.852	<.001	<.001	3	11
SKIN	Nucleotide biosynthetic process →	+0.071	+1.842	<.001	.001	3	10
LUNG_SCLC	Purine-containing compound biosynthetic process →	+0.066	+1.612	<.001	.003	3	10
LUNG_SCLC	Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator →	+0.090	+1.525	.002	.002	3	9
LUNG_SCLC	Nucleoside phosphate biosynthetic process →	+0.054	+1.506	.004	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,595 associations by consensus.

Purine nucleotide biosynthetic process by CGREF1 expression — OVARY

Explore this box plot interactively →