CGN

Across TCGA pan-cancer cohorts, CGN mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CGN data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CGN mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CGN expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where CGN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	All	1.000	0.835	.036	66	view →
PDAC	DFS	Tertile	All	0.606	0.290	<.001	54	view →
LUAD	DFS	Median	II,III,IV	0.190	0.810	.001	7	view →
UCEC	DFS	Median	All	1.000	0.936	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CGN–COAD (DFS)

Open the COAD breakdown →