CGN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CGN RNA expression is significantly associated with the protein abundance of many other proteins, with 13,211 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CGN-associated proteins across cancer lineages are CGN_S155, CGN_S165, and CGN_S120. Each is linked with CGN in more than 8 cancer types. Because this analysis shows association rather than direction, both CGN-to-partner and partner-to-CGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CGN versus CGN_S155 in HNSC, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CGN→partner) and Y-score (partner→CGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCGN_S155 →+0.931+1.210<.001<.00139
BRCACGN_S165 →+1.225+1.450<.001<.00139
LSCCCGN_S120 →+1.117+1.206<.001<.00137
BRCACGN_S338 →+1.310+1.070<.001<.00137
BRCACGN_S96 →+1.178+2.047<.001<.00137
BRCALLGL2 →+0.547+1.005<.001.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,211 associations by consensus.

CGN vs CGN_S155 — HNSC

Per-sample scatter of CGN vs CGN_S155 in HNSC (Pearson r = 0.78).

Explore this scatter interactively →

Exploration