CGN

Across TCGA patient cohorts, CGN protein abundance is significantly associated with the RNA expression of many other genes, with 11,002 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CGN-associated genes across cancer lineages are PRRX1, PLEKHA6, and BASP1. Each is linked with CGN in more than 4 cancer types. Because this analysis shows association rather than direction, both CGN-to-partner and partner-to-CGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CGN versus PRRX1 in OV, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGN→partner) and Y-score (partner→CGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PRRX1 →	-1.501	-0.497	.001	.001	3	5
PDAC	PLEKHA6 →	+0.721	+0.488	<.001	<.001	3	5
OV	BASP1 →	-1.311	-0.493	<.001	.004	3	5
LSCC	SNAI2 →	-1.058	-0.558	<.001	<.001	3	5
UCEC	ERBB3 →	+0.928	+0.645	<.001	<.001	3	5
COAD	TTC39A →	+0.787	+0.400	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,002 associations by consensus.

CGN vs PRRX1 — OV

Explore this scatter interactively →