CGGBP1

Across TCGA patient cohorts, CGGBP1 mutation is significantly associated with the RNA expression of many other genes, with 2,972 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CGGBP1-associated genes across cancer lineages are TRIM51BP, RNA5SP411, and RNA5SP412. Each is linked with CGGBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGGBP1-to-partner and partner-to-CGGBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM51BP grouped by CGGBP1-low versus CGGBP1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGGBP1→partner) and Y-score (partner→CGGBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRIM51BP →	+0.499	+5.345	<.001	.001	3	2
UCEC	RNA5SP411 →	+0.779	+1.730	<.001	.001	3	2
UCEC	RNA5SP412 →	+0.532	+2.104	<.001	<.001	3	2
CESC	LINC02559 →	+1.600	+5.342	<.001	.002	3	2
UCEC	RNA5SP422 →	+0.517	+1.808	<.001	.001	3	2
CESC	C2orf69P2 →	+0.059	+5.569	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,972 associations by consensus.

TRIM51BP by CGGBP1 expression — CESC

Explore this box plot interactively →