CGB7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CGB7 mutation is significantly associated with the RNA expression of many other genes, with 327 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CGB7-associated genes across cancer lineages are MIR7702, RNU4-17P, and CTDSPL2P1. Each is linked with CGB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGB7-to-partner and partner-to-CGB7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGB7→partner) and Y-score (partner→CGB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR7702 →+0.284+4.601<.001.00332
HNSCRNU4-17P →+0.203+7.954<.001.00832
SKCMCTDSPL2P1 →+0.027+5.680<.001.00332
UCECNFYBP1 →+0.310+2.674<.001.00132
UCECRPL23P11 →+0.133+2.666<.001.00132
UCECPTP4A1P7 →+0.155+2.171.006.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 327 associations by consensus.

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