CGB1

Across TCGA patient cohorts, CGB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CGB1-associated GO terms across cancer lineages are [2Fe-2S] cluster assembly, Outer mitochondrial membrane organization, and Ribose phosphate biosynthetic process. Each is linked with CGB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CGB1-to-partner and partner-to-CGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [2Fe-2S] cluster assembly grouped by CGB1-low versus CGB1-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CGB1→partner) and Y-score (partner→CGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	[2Fe-2S] cluster assembly →	+0.050	+0.030	<.001	<.001	3	6
STAD	Outer mitochondrial membrane organization →	+0.068	+0.030	<.001	.002	3	5
STAD	Ribose phosphate biosynthetic process →	+0.061	+0.030	<.001	<.001	1	7
HNSC	Regulation of immunoglobulin production →	+0.035	+0.011	<.001	<.001	3	4
KIRC	Positive regulation of telomere maintenance →	+0.043	+0.009	<.001	.001	3	4
STAD	Regulation of protein kinase C signaling →	+0.055	+0.029	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,150 associations by consensus.

[2Fe-2S] cluster assembly by CGB1 expression — UCEC

Explore this box plot interactively →