CGB1

Across TCGA patient cohorts, CGB1 mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CGB1-associated genes across cancer lineages are RN7SL847P, RNA5SP394, and MIR208B. Each is linked with CGB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGB1-to-partner and partner-to-CGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL847P grouped by CGB1-low versus CGB1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGB1→partner) and Y-score (partner→CGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL847P →	+0.254	+5.595	<.001	<.001	3	2
CESC	RNA5SP394 →	+0.497	+5.345	<.001	.001	3	2
LUSC	MIR208B →	+0.576	+5.151	<.001	.007	3	2
LUSC	RNA5SP162 →	+1.213	+5.211	<.001	.007	3	2
CESC	CTXN2 →	+0.039	+4.601	.001	.004	3	1
CESC	LINC02559 →	+0.444	+5.342	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

RN7SL847P by CGB1 expression — CESC

Explore this box plot interactively →