CFP

Across TCGA pan-cancer cohorts, CFP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CFP data layer compared with 28 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CFP mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CFP expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

PDAC, LUAD, and CCRCC are the cancer types where CFP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.792	0.900	.002	22	view →
LUAD	OS	Median	II,III,IV	0.306	0.853	.001	11	view →
CCRCC	OS	Median	III,IV	0.968	0.672	.005	9	view →
GBM	DFS	Tertile	All	0.458	0.163	.023	4	view →
HNSC	DFS	Median	II,III,IV	0.562	0.754	.022	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CFP–PDAC (OS)

Open the PDAC breakdown →