CFP

Across TCGA cell cohorts, CFP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,663 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CFP-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Negative regulation of translational initiation, and Regulation of telomere maintenance via telomerase. Each is linked with CFP in more than 9 cancer types. Because this analysis shows association rather than direction, both CFP-to-partner and partner-to-CFP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by CFP-low versus CFP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFP→partner) and Y-score (partner→CFP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.174	+0.552	<.001	.003	3	10
SOFT_TISSUE	Negative regulation of translational initiation →	+0.090	+0.367	<.001	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance via telomerase →	+0.059	+0.259	.003	.003	3	10
BONE	Subtelomeric heterochromatin formation →	+0.149	+0.587	<.001	.001	3	9
SOFT_TISSUE	Regulation of RNA splicing →	+0.089	+0.273	<.001	<.001	3	9
BLOOD_Myeloma	Regulation of chromosome segregation →	+0.084	+0.741	.004	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,663 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by CFP expression — BONE

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