CFLAR

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CFLAR RNA expression is significantly associated with the protein abundance of many other proteins, with 15,332 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CFLAR-associated proteins across cancer lineages are MYO1G, APOL3, and PARP14. Each is linked with CFLAR in more than 5 cancer types. Because this analysis shows association rather than direction, both CFLAR-to-partner and partner-to-CFLAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFLAR versus MYO1G in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CFLAR→partner) and Y-score (partner→CFLAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMYO1G →+0.438+0.364<.001<.00136
HNSCAPOL3 →+0.578+0.362<.001<.00135
LSCCPARP14 →+0.412+0.471<.001<.00135
GBMPRKCD →+0.323+0.426<.001<.00135
LSCCVAV1 →+0.461+0.332<.001<.00135
LSCCPTPN7 →+0.380+0.402<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,332 associations by consensus.

CFLAR vs MYO1G — GBM

Per-sample scatter of CFLAR vs MYO1G in GBM (Pearson r = 0.44).

Explore this scatter interactively →

Exploration