CFL2

Across TCGA patient cohorts, CFL2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,157 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CFL2-associated genes across cancer lineages are AKAP6, LMOD1, and EMCN. Each is linked with CFL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CFL2-to-partner and partner-to-CFL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFL2 versus AKAP6 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFL2→partner) and Y-score (partner→CFL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AKAP6 →	+0.957	+0.724	<.001	.001	3	8
UCEC	LMOD1 →	+1.805	+0.689	<.001	<.001	3	8
CCRCC	EMCN →	+1.192	+0.347	<.001	<.001	3	8
HNSC	PDE2A →	+0.990	+1.374	<.001	<.001	3	8
HNSC	ABCC9 →	+1.536	+1.277	<.001	<.001	3	8
CCRCC	FHL5 →	+1.086	+0.343	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,157 associations by consensus.

CFL2 vs AKAP6 — UCEC

Explore this scatter interactively →