Across TCGA patient cohorts, CFL1P1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFL1P1-associated genes across cancer lineages are GML, MIR8078, and EIF1AY. Each is linked with CFL1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFL1P1-to-partner and partner-to-CFL1P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFL1P1→partner) and Y-score (partner→CFL1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GML →	+0.092	+3.302	.005	.009	3	1
UCEC	MIR8078 →	+0.697	+3.106	.002	.007	3	1
UCEC	EIF1AY →	+0.043	+3.204	<.001	.006	3	1
UCEC	RNU1-100P →	+0.482	+3.233	.001	.005	3	1
UCEC	RNU6-1292P →	+0.504	+4.132	<.001	.009	3	1
UCEC	RNY4P13 →	+0.189	+5.738	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

CFL1P1 survival (RNA) · tumor vs normal (RNA) · all CFL1P1 data types