CFL1

Across TCGA patient cohorts, CFL1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,959 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CFL1-associated genes across cancer lineages are SIPA1, FCGR1A, and COX6CP17. Each is linked with CFL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CFL1-to-partner and partner-to-CFL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFL1 versus SIPA1 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFL1→partner) and Y-score (partner→CFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SIPA1 →	+0.590	+0.207	<.001	<.001	3	5
UCEC	FCGR1A →	+1.133	+0.195	<.001	.002	3	4
UCEC	COX6CP17 →	+0.932	+0.156	.003	.007	3	4
HNSC	TMEM183A →	-0.456	-0.217	<.001	.004	3	4
GBM	FCGR3A →	+1.131	+0.199	<.001	<.001	3	4
HNSC	ADNP2 →	-0.460	-0.266	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,959 associations by consensus.

CFL1 vs SIPA1 — UCEC

Explore this scatter interactively →