Across TCGA patient cohorts, CFI RNA expression is significantly associated with the protein abundance of many other proteins, with 19,471 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CFI-associated proteins across cancer lineages are DAB2_S723, DPYD, and ESF1_S153. Each is linked with CFI in more than 5 cancer types. Because this analysis shows association rather than direction, both CFI-to-partner and partner-to-CFI results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CFI→partner) and Y-score (partner→CFI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DAB2_S723 →	+0.911	+0.704	<.001	<.001	3	6
GBM	DPYD →	+0.815	+0.858	<.001	<.001	3	6
LSCC	ESF1_S153 →	-0.785	-0.511	<.001	<.001	3	6
GBM	GPX8 →	+0.688	+0.786	<.001	.001	3	6
LSCC	RAI14 →	+0.351	+0.642	<.001	<.001	3	6
GBM	NNMT →	+1.009	+0.761	.005	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,471 associations by consensus.

Exploration

CFI survival (RNA) · tumor vs normal (RNA) · all CFI data types