Across TCGA patient cohorts, CFI protein abundance is significantly associated with the RNA expression of many other genes, with 10,857 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CFI-associated genes across cancer lineages are DIPK2B, F13A1, and FAP. Each is linked with CFI in more than 5 cancer types. Because this analysis shows association rather than direction, both CFI-to-partner and partner-to-CFI results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFI→partner) and Y-score (partner→CFI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DIPK2B →	+0.726	+0.620	<.001	<.001	3	6
GBM	F13A1 →	+1.968	+0.482	<.001	<.001	3	6
COAD	FAP →	+1.097	+0.564	<.001	<.001	3	6
UCEC	LRRC4C →	+0.885	+0.304	<.001	.004	3	5
BRCA	FCER1A →	+1.271	+0.522	<.001	<.001	3	5
GBM	TIMP1 →	+1.187	+0.430	.008	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,857 associations by consensus.

Exploration

CFI survival (RNA) · tumor vs normal (RNA) · all CFI data types